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Health & Life Sciences  >  2008 HP Health and Life Sciences Symposium

Technical Breakouts Abstracts

Health & Life Sciences Symposium IV, 2008
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HP 


Patient Information – Integrating Disparate Reality 
Speaker:
Adrienne Tannenbaum, Senior Principal, Hewlett-Packard Company

In this presentation Adrienne Tannenbaum discusses today’s patient tracking issues. Specifically, she presents the various ways patient information can be created, described, enhanced, removed, and copied with today’s lack of information integrity. She will then discuss the reasons – and present the requirements for a solution. Topics discussed include:

  • What is a “patient”?
  • Why must all patients be equal?
  • The way it is
  • The way it should be

Today’s efforts toward creating a Common Patient Record will also be discussed.


»  View the presentation (PDF, 9.73MB)

Asklepios


Asklepios Future Hospital
Speaker: Jörg Focke, Head of Innovation Center, Asklepios Future Hospital

This session will discuss the impact of standards on the healthcare market. We will review a recent case study at Asklepios that demonstrates:

  • Asklepios Future Hospital Program – a place and fight for standards
  • The impact of standards on the healthcare-market (OneIT, Healthcare-IT, medical interconnect)
  • The case: eye-clinics at Asklepios Hospital Barmbek (Hamburg, Germany) Status quo of the evaluation, first results, value added benefits for patients, doctors, clinical performance and first ROI-expectations

Included is the role that HP has in this project and in the whole Asklepios-Future-Hospital-Program as one of the largest innovation-initiatives in healthcare worldwide.


»  View the presentation (PDF, 30.8MB)

HP


Strategies for Effectively Managing a Print and Capture Environment in Healthcare
Speakers: Jason Hansen, IPG BPC Healthcare, Hewlett-Packard Company

Learn about HP’s portfolio of services and software for creating secure, easy to manage, cost effective ways to implement a distributed print and capture environment for healthcare, with an emphasis on the new Patient Identification Printing solution. Discover strategies to optimize document output delivery to reduce the number printed pages and support costs.


»  View the presentation (PDF, 16.5MB)

deCODE Genetics, Inc.


From Population Genetics to Personalized Genetics
Speaker:
Hákon Guðbjartsson, Ph.D., Vice President Informatics, deCODE Genetics Inc.

deCODE genetics has carried out population based genetic research in Iceland for over ten years and is currently an undisputed leader in genetic discovery of common diseases. In the past, these genetic discoveries have been used to target specific biological pathways for drug development, diagnostic products and, now more recently, also in a web based personalized genetic services named deCODEme.com. This presentation provides the informatics perspective on how deCODE has leveraged its unique population resource in Iceland. An overview of some of the informatics solutions deCODE has developed to capture and analyze its clinical, genetic and the comprehensive Icelandic genealogical data will be presented. Finally, we will describe how deCODE is translating its research findings towards personalized medicine and preventive healthcare.


»  View the presentation (PDF, 22.2MB)

Lilly Singapore Centre for Drug Discovery


Title: Data Integration Challenges and Best Practices at Lilly Singapore Centre for Drug
Discovery: Integrated Genomics Portal for Cancer Research

Speaker:  JianYang, IT manager, Lily Singapore Centre for Drug Discovery

Drug target identification and validation are complex tasks increasingly involving use of information from high throughput technologies. The diversity of genomic datasets generated with microarrays and the advanced analysis techniques required to derive meaningful results from such datasets may be unfamiliar and uncomfortable to ordinary biologists. This can limit exploring the benefits from such technologies in their entirety. An outcome is the improper and under utilization of the datasets generated. IGPCR (Integrated Genomics Portal for Cancer Research) is an integrated .Net application that summarizes analysis results from both proprietary and public data including mutations, array comparative genomic hybridization (aCGH), gene expression from cell lines and tumors as also RNAi data relevant for cancer research. This is accomplished with user friendly outputs and visualization such as tables, heatmaps and graphs. IGPCR utilizes Microsoft Composite UI Application Block (CAB) architecture and it accesses different databases using Windows or Java web service. The different data types are organized as tabs. A single query for a gene retrieves results obtained from analysis of different datasets in an asynchronous fashion. Besides, single gene search, users can create custom lists of genes and query both public cell line expression datasets such as the National Cancer Institute (NCI) and Lilly proprietary datasets with one click. IGPCR provides analysis tools like survival analysis that help determine whether expression levels of a gene affect the survival probability of the patient, a key determinant in target prioritization. IGPCR as an integrated desktop portal is being used by Lilly cancer researchers to identify new drug targets, prioritize existing targets and to identify appropriate cell line models for experiments. In summary IGPCR helps improve the productivity of cancer scientists while providing a framework that is extensible to other therapeutic areas and data from emerging technologies such as ChIP on Chip.


»  View the presentation (PDF, 16.3MB)

HP


Data Transformation—Complexities and Solutions in Healthcare
Speaker: Geraldine Wade, M.D., M.S., Director of Medical Informatics, Hewlett-Packard Company

How do we transform the vast volumes of disparate healthcare data so that it can be aggregated and analyzed, be interoperable within an enterprise and beyond in order to improve patient care, enhance business operations, satisfy compliance concerns and drive innovation? The complexities of healthcare data require transformation to go beyond simple ETL processes and require a combination of people, processes and tools.

Healthcare data needs to be understood in context from the point of data capture.

Data transformation must consider interoperability components such as common data elements, vocabularies and information models. Other important factors include how we define quality measures and what data standards we want to adopt while acknowledging some uncertainty and an industry in flux. There is a need to look at the bigger picture of how data can be transformed over time, what data has the greatest “value” and how applications can be expanded to harmonize with the growing body of knowledge from different focus areas including healthcare delivery, biopharma, genomics, molecular biology, etc. Solutions include understanding an organization’s pain points and goals and are often centered on “Use Cases”. Recommendations for new technologies should strive to include non-proprietary interoperable components. Setting realistic expectations and getting consensus from stakeholders are critical success factors in the data transformation process.


»  View the presentation (PDF, 8.06MB)

HP


Product Tracking and Authentication
Speaker: Iain MacNeil, Business Development Manager, PT&A World Wide Health and Life Science

HP’s Product Tracking & Authentication (PT&A) Solution Portfolio is built on our leading innovation in print technologies and a long history of success in Global Supply Chain and Enterprise ERP integration. The portfolio specifically targets the emerging regulatory requirements, while identifying unique opportunities to increase efficiency, reduce operating cost, and improve overall brand protection.

In our own experience, HP has delivered over 600 million serialized products to 35 countries and has been recognized as one of the top leaders in anti-counterfeiting and brand protection. Four years ago, HP launched our PT&A Center of Excellence in Puerto Rico and has been collaborating with local pharmaceutical manufacturers to continually evolve this portfolio.

Last year, HP joined with other industry leaders including Supplyscape, Systech, and Nosco to form the California Express Solutions Team (CEST). The team’s goal was to educate our customers on the changing landscape of state, federal, and global ePedigree and Serialization requirements. This year, we have expanded the team’s membership and are laser focused on helping our customers determine the “how to” in their pursuit of regulatory compliance.

The CEST team is currently engaged with numerous Pharmaceutical and BioTech customers delivering Blueprints, Pilots, and long term value roadmaps to address these demands.


»  View the presentation (PDF, 17.9MB)

Google, InSTEDD


Biosurveillance
Speaker:
Taha Kass-Hout, M.D., M.S., Director, Health Informatics, Google, InSTEDD

Dating back to Hippocrates, biosurveillance, the detection and observation of disease outbreaks, is not an entirely new concept. In recent history, the geographical isolation between plants and animals has been gradually broken by the intentional or natural transport of organisms caused by human travel, tourism or trade. Today, the rate at which species are moving between different bio-geographic regions is unprecedented, resulting in adverse ecological, economic, and human health consequences. Additionally, global environmental changes have continued to grow rapidly throughout the past five years. These changes for example to climate, transport networks, disease pathogens and their vectors do not respect administrative boundaries and their influences and impacts are best addressed at the global scale. These factors have contributed to an environment where a new disease threat can spread globally within hours and days. Over the last decade, automated biosurveillance systems have been developed to provide more timely detection of disease outbreaks by monitoring clinical systems and other sources. To date, the bulk of these systems have been regionally deployed, limited to areas where clinical data is readily available, and Internet connectivity and high bandwidth are widespread. Unfortunately, these systems do not support regions of low bandwidth, limited connectivity, and sparse use of clinical information systems-the regions where globe-threatening outbreaks typically originate and where timely interventions are most needed. What is needed now is a global information network and scientific methods to support timely detection and monitoring of events world-wide, as close to real time as possible.

This presentation is not available



Crospon Medical Devices


A Shot in the Arm for Inkjet Technology
Speaker: John O’Dea, Chief Executive Officer, Crospon Medical Devices

The possibility of personalised painless drug delivery devices has moved one step closer with the recent licensing of certain aspects of HP ink-jet technology to Crospon, an Irish medical device company. A number of practical issues need to be overcome for this technology to be transported from the information technology to the medical device arena. This presentation will talk about the different aspects of the licensed technology, and how HP are now actively undertaking licensing different technologies to companies, large or small. The potential of the technology along with the barriers that exist to successfully transport it into a drug delivery application will also be discussed.


»  View the presentation (PDF, 4.72MB)

M.D. Anderson Cancer Center and HP


Enabling Translational Medicine – An M.D. Anderson/Hewlett-Packard Project
Speaker:  Dr. Krishna Sankavaram, Director for Research IT, M.D. Anderson Cancer Center
Speaker:  David Medina, Director, Pharmaceutical and Life Science Markets, Worldwide Health and Life Sciences Technology Solutions Group, Hewlett-Packard Company

This presentation will discuss a joint project between M.D. Anderson Cancer Center and Hewlett-Packard to develop a unique tool to easily access and analyze genomic and clinical data. The project known as TREx (Translation Research Extensible Platform) is an SOA-based platform designed to enable clinical researchers and bioinformatics professionals to discover relationships and develop basic hypotheses from the various forms of genomic, proteomic and tissue data available at MDACC.

This presentation is not available




Vital-IT Group


Integration of Biological Knowledge: From Avalanche of Data to System Modeling
Speaker: Dr. Ioannis Xenarios, Ph.D., Director of Vital-IT Group, Swiss Institute of Bioinformatics

The face of biological and medical research has evolved at an alarming rate. From a one-gene/one-protein analysis it has borne witness to a multitude of new technologies that allow us to capture and integrate a vast amount of information generated by high throughput methods such as DNA microarrays, proteomics and bioinformatics and more recently ultra high throughput sequencing. Then along came the sequenced human genome and suddenly we have a complete skeleton upon which to integrate the mass of information generated. The scientific community now has an integrated way of looking at what have previously been isolated snippets of knowledge. We have known for some time the function(s) of many proteins in signaling pathways, developmental

regulation, cell cycle progression and so on. However, what is becoming clearer as we gather more information, and gaze upon the global picture, is that a single protein rarely performs a single function. Rather, the activity that we assign to it is the product of its interaction with other proteins, small molecules or nucleic acids at any given time. Despite the advance in high throughput technologies (or, perhaps because of this), we are faced with an avalanche of data but only flakes of knowledge. What we aim to offer is a system approach that would enable us to integrate all the information generated from these technology platforms and develop both mathematical and biological methodologies to test them.


»  View the presentation (PDF, 20.2MB)


HP


Storage Trends and their Implications to the Datacenter
Speaker:
  Abbott Schindler, Senior Technologist, Hewlett-Packard Company

Storage systems are becoming more intelligent and being equipped with new functionality. Storage virtualization continues to be a major topic, with new twists around server virtualization. Storage networks and the way data gets delivered to applications is changing. And surrounding this all is a plethora of management concerns. This session will clarify the important issues around these topics and how technology evolution may shape up over the next several years. Against this backdrop, attendees will learn about HP’s storage strategy and how it will apply technologies to deliver extremely interesting storage solutions in the near- and long-term.


»  View the presentation (PDF, 11.4MB)
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